|
rs2069837
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Previous work has revealed a genetic association between Takayasu arteritis and a non-coding genetic variant in an enhancer region within <i>IL6</i> (rs2069837 A/G).
|
31315839 |
2019 |
|
rs2099684
|
|
C |
0.710 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs103294
|
|
T |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs117298325
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs17133698
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs1713450
|
|
C |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs2322599
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs4817988
|
|
G |
0.700 |
GeneticVariation |
GWASCAT |
Genetic determinants and an epistasis of LILRA3 and HLA-B*52 in Takayasu arteritis.
|
30498034 |
2018 |
|
rs2476601
|
|
|
0.020 |
GeneticVariation |
BEFREE |
This is the first report documenting an association between PTPN22 R620W and TA.
|
30470857 |
2019 |
|
rs33996649
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our data showed that the PTPN22 R620W polymorphism is a risk factor for TA (CC vs. CT: OR 4.3, p = 0.002, and C vs. T: OR 4.1, p = 0.003); however, the PTPN22 R263Q and - 1123G/C polymorphisms are not associated with this AD.
|
30470857 |
2019 |
|
rs665268
|
|
|
0.020 |
GeneticVariation |
BEFREE |
MLX-Q139R mutation plays a crucial role in the pathogenesis of TAK through promoting inflammasome formation.
|
30354298 |
2018 |
|
rs1205
|
|
|
0.010 |
GeneticVariation |
BEFREE |
T allele of rs1205 in CRP gene was less frequent in TA.
|
29024426 |
2018 |
|
rs6871626
|
|
|
0.050 |
GeneticVariation |
BEFREE |
A previous study revealed the association between susceptibility to Takayasu arteritis (TAK) and a single nucleotide polymorphism (SNP) rs6871626 located in IL12B, which encodes interleukin (IL)-12p40, a common component of IL-12p70 and IL-23.
|
28874185 |
2017 |
|
rs6871626
|
|
|
0.050 |
GeneticVariation |
BEFREE |
IL12B rs6871626 did not show an association with IBD-TA compared with that with TA without IBD.
|
28449344 |
2017 |
|
rs1800795
|
|
|
0.010 |
GeneticVariation |
BEFREE |
GG genotypes of rs1800795 in IL-6 was also associated with occurrence of tuberculosis in our patients with TA.
|
28438554 |
2018 |
|
rs763780
|
|
|
0.010 |
GeneticVariation |
BEFREE |
G allele of rs763780 in IL-17F gene was protectively associated against susceptibility to TA.
|
28438554 |
2018 |
|
rs1264457
|
|
|
0.010 |
GeneticVariation |
BEFREE |
sHLA-E level is useful as a biomarker of disease activity and course in TA patients. rs1264457 polymorphism is neither associated with susceptibility nor did it influence sHLA-E levels in TA.
|
28425192 |
2018 |
|
rs12524487
|
|
|
0.720 |
GeneticVariation |
BEFREE |
Our findings indicated that rs12524487 in HLA-B/MICA was a genetic risk factor for TA in a Chinese Han population and rs9366782 in this region was associated with ischemic brain disease in TA but not TA susceptibility.
|
28261975 |
2018 |
|
rs114202986
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs3763288 and rs114202986 in MICA were negatively related to TA either as a whole or in any clinical features.
|
28261975 |
2018 |
|
rs3763288
|
|
|
0.010 |
GeneticVariation |
BEFREE |
However, rs3763288 and rs114202986 in MICA were negatively related to TA either as a whole or in any clinical features.
|
28261975 |
2018 |
|
rs9366782
|
|
|
0.010 |
GeneticVariation |
BEFREE |
Our findings indicated that rs12524487 in HLA-B/MICA was a genetic risk factor for TA in a Chinese Han population and rs9366782 in this region was associated with ischemic brain disease in TA but not TA susceptibility.
|
28261975 |
2018 |
|
rs6871626
|
|
|
0.050 |
GeneticVariation |
BEFREE |
We demonstrated a allele association between the four SNPs of IL12B and TA (rs6871626: OR 1.52, 95% CI 1.26-1.83; rs4921492: OR 1.46, 95% CI 1.21-1.75; rs60689680: OR 1.41, 95% CI 1.17-1.69; rs4921493: OR 1.45, 95% CI 1.21-1.75, all P <sub>c</sub> < 10<sup>- 3</sup> ).
|
28160070 |
2017 |
|
rs4921492
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We demonstrated a allele association between the four SNPs of IL12B and TA (rs6871626: OR 1.52, 95% CI 1.26-1.83; rs4921492: OR 1.46, 95% CI 1.21-1.75; rs60689680: OR 1.41, 95% CI 1.17-1.69; rs4921493: OR 1.45, 95% CI 1.21-1.75, all P <sub>c</sub> < 10<sup>- 3</sup> ).
|
28160070 |
2017 |
|
rs4921493
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We demonstrated a allele association between the four SNPs of IL12B and TA (rs6871626: OR 1.52, 95% CI 1.26-1.83; rs4921492: OR 1.46, 95% CI 1.21-1.75; rs60689680: OR 1.41, 95% CI 1.17-1.69; rs4921493: OR 1.45, 95% CI 1.21-1.75, all P <sub>c</sub> < 10<sup>- 3</sup> ).
|
28160070 |
2017 |
|
rs60689680
|
|
|
0.010 |
GeneticVariation |
BEFREE |
We demonstrated a allele association between the four SNPs of IL12B and TA (rs6871626: OR 1.52, 95% CI 1.26-1.83; rs4921492: OR 1.46, 95% CI 1.21-1.75; rs60689680: OR 1.41, 95% CI 1.17-1.69; rs4921493: OR 1.45, 95% CI 1.21-1.75, all P <sub>c</sub> < 10<sup>- 3</sup> ).
|
28160070 |
2017 |